Photo appears in the artwork for The Last Tour on Earth album
Marilyn Manson 1998/99 Mechanical Animals tour

Marilyn Manson onstage

Marilyn singing:
"I Don't Like The Drugs But The Drugs Like Me"

Here's another take on that same stage set. This may be a fan photo but I got it from the official site and they didn't show any credits.

Marilyn Manson band onstage

Good overview of the band onstage, and shows the backing singers, far right.

I read that the DRUGS sign is 40 feet wide (12m) by 5 feet high (1.5m)
and each letter has 150 clear, 75 watt bulbs in it.

photo page